Sophie Piperno-Neumann Selected Research

sotrastaurin

1/2020	Genomic Profiling of Metastatic Uveal Melanoma and Clinical Results of a Phase I Study of the Protein Kinase C Inhibitor AEB071.
6/2016	Dual inhibition of protein kinase C and p53-MDM2 or PKC and mTORC1 are novel efficient therapeutic approaches for uveal melanoma.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Sophie Piperno-Neumann Research Topics

Disease

30	Neoplasms (Cancer) 01/2022 - 05/2004
26	Sarcoma (Soft Tissue Sarcoma) 01/2022 - 08/2006
23	Uveal melanoma 11/2022 - 04/2010
17	Neoplasm Metastasis (Metastasis) 11/2022 - 02/2011
14	Osteosarcoma (Osteogenic Sarcoma) 01/2022 - 11/2015
9	Leiomyosarcoma 01/2022 - 08/2006
8	Melanoma (Melanoma, Malignant) 11/2022 - 12/2005
7	Breast Neoplasms (Breast Cancer) 01/2022 - 05/2004
6	Neutropenia 01/2022 - 03/2015
6	Disease Progression 01/2021 - 04/2015
5	Fatigue 01/2022 - 04/2015
5	Hemangiosarcoma (Angiosarcoma) 09/2015 - 11/2008
4	Hypertension (High Blood Pressure) 01/2021 - 12/2016
3	Thrombocytopenia (Thrombopenia) 01/2022 - 04/2015
3	Liposarcoma 01/2022 - 12/2016
2	Nausea 01/2022 - 01/2018
2	Febrile Neutropenia 01/2022 - 04/2015
2	Exanthema (Rash) 01/2021 - 01/2018
2	Pruritus (Itching) 01/2021 - 01/2018
2	Asthenia 01/2021 - 12/2016
2	Aggressive Fibromatosis (Desmoid) 12/2020 - 01/2019
2	Phyllodes Tumor (Cystosarcoma Phylloides) 06/2020 - 05/2020
2	Margins of Excision 06/2020 - 01/2019
2	Ewing Sarcoma (Sarcoma, Ewing) 01/2020 - 01/2019
2	Cicatrix (Scar) 01/2019 - 07/2013
2	Synovial Sarcoma (Synovioma) 01/2018 - 12/2016
1	Heart Failure 01/2022
1	Chondrosarcoma 01/2021
1	Fever (Fevers) 01/2021
1	Liver Diseases (Liver Disease) 01/2021
1	Pneumothorax 01/2020
1	Leukopenia 01/2020
1	Mucositis 01/2020
1	Carcinogenesis 12/2019
1	Chest Pain (Chest Pains) 01/2019
1	Hepatocellular Carcinoma (Hepatoma) 01/2019

Drug/Important Bio-Agent (IBA)

9	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022 - 08/2006
6	TrabectedinIBA 01/2022 - 04/2014
5	Biological ProductsIBA 01/2022 - 04/2010
5	Proteins (Proteins, Gene)FDA Link 01/2020 - 02/2011
5	Ifosfamide FDA LinkGeneric 01/2020 - 08/2006
5	Paclitaxel (Taxol)FDA LinkGeneric 01/2017 - 06/2004
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 03/2014
4	regorafenibIBA 01/2021 - 12/2016
4	Methotrexate (Mexate)FDA LinkGeneric 01/2020 - 01/2018
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019 - 09/2014
3	RNA (Ribonucleic Acid)IBA 01/2022 - 02/2016
3	Dacarbazine (DIC)FDA LinkGeneric 01/2021 - 01/2018
3	Etoposide (VP 16)FDA LinkGeneric 01/2020 - 01/2018
3	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 07/2012
3	Pharmaceutical PreparationsIBA 07/2019 - 01/2018
3	Bevacizumab (Avastin)FDA Link 01/2017 - 09/2015
3	Sorafenib (BAY 43-9006)FDA Link 11/2014 - 01/2012
3	Gemcitabine FDA Link 01/2012 - 11/2005
3	Docetaxel (Taxotere)FDA Link 01/2012 - 05/2004
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2020 - 03/2015
2	Protein Kinase CIBA 01/2020 - 06/2016
2	sotrastaurinIBA 01/2020 - 06/2016
2	Cisplatin (Platino)FDA LinkGeneric 01/2020 - 01/2020
2	Immune Checkpoint InhibitorsIBA 06/2019 - 01/2018
2	NucleotidesIBA 01/2019 - 10/2013
2	AZD 6244IBA 04/2018 - 01/2018
2	Zoledronic Acid (Zometa)FDA Link 01/2017 - 08/2016
2	AnthracyclinesIBA 12/2016 - 05/2004
2	Everolimus FDA Link 06/2016 - 12/2014
2	Phosphoric Monoester Hydrolases (Phosphatases)IBA 04/2016 - 02/2011
2	Protein Tyrosine PhosphatasesIBA 04/2016 - 02/2011
2	Temozolomide (Temodar)FDA LinkGeneric 03/2016 - 04/2010
2	Alanine Transaminase (SGPT)IBA 04/2015 - 03/2015
2	Neoplasm Antigens (Tumor Antigens)IBA 04/2014 - 04/2010
2	Circulating Tumor DNAIBA 03/2014 - 07/2012
2	Cytotoxins (Cytolysins)IBA 01/2012 - 08/2006
2	taxaneIBA 06/2004 - 05/2004
1	Laminin (Merosin)IBA 11/2022
1	Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)IBA 11/2022
1	Phenobarbital (Luminal)FDA Link 01/2022
1	selinexorIBA 01/2022
1	pembrolizumabIBA 01/2021
1	RNA Splicing FactorsIBA 01/2021
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2021
1	tebentafuspIBA 01/2021
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2021
1	Glycoproteins (Glycoprotein)IBA 01/2021
1	HLA-A Antigens (HLA-A)IBA 01/2021
1	CytokinesIBA 01/2021
1	IpilimumabIBA 01/2021
1	CateninsIBA 12/2020
1	Alkylating AgentsIBA 05/2020
1	cabozantinibIBA 01/2020
1	trofosfamideIBA 01/2020
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 06/2019

Therapy/Procedure

26	Therapeutics 01/2022 - 05/2004
25	Drug Therapy (Chemotherapy) 01/2022 - 05/2004
5	Radiotherapy 02/2021 - 07/2013
2	Immunotherapy 01/2022 - 01/2018
2	Aftercare (After-Treatment) 01/2019 - 06/2014
2	Neoadjuvant Therapy 01/2019 - 04/2014
2	Off-Label Use 11/2015 - 11/2014
1	Adjuvant Chemotherapy 06/2020
1	Combination Drug Therapy (Combination Chemotherapy) 01/2019